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Estimation of immune cell content in tumor using single-cell RNA-seq reference data

BACKGROUND: The rapid development of single-cell RNA sequencing (scRNA-seq) provides unprecedented opportunities to study the tumor ecosystem that involves a heterogeneous mixture of cell types. However, the majority of previous and current studies related to translational and molecular oncology hav...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoqing, Chen, Y. Ann, Conejo-Garcia, Jose R., Chung, Christine H., Wang, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642583/
https://www.ncbi.nlm.nih.gov/pubmed/31324168
http://dx.doi.org/10.1186/s12885-019-5927-3