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Antitumor effect of hyaluronic-acid-modified chitosan nanoparticles loaded with siRNA for targeted therapy for non-small cell lung cancer

Purpose: Nanoparticle (NP)-mediated targeted delivery of therapeutic genes or siRNAs to tumors has potential advantages. In this study, hyaluronic acid (HA)-modified chitosan nanoparticles (CS NPs-HA) loaded with cyanine 3 (Cy3)-labeled siRNA (sCS NPs-HA) were prepared and characterized. Methods: Hu...

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Detalles Bibliográficos
Autores principales: Zhang, Wenhua, Xu, Wenhua, Lan, Yu, He, Xuliang, Liu, Kaibin, Liang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642624/
https://www.ncbi.nlm.nih.gov/pubmed/31406460
http://dx.doi.org/10.2147/IJN.S203113