Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis

Renal tubulointerstitial fibrosis is the final common pathway in end-stage renal disease and is characterized by aberrant accumulation of extracellular matrix (ECM) components secreted by myofibroblasts. Tubular type 2 EMT, induced by TGF-β, plays an important role in renal fibrosis, by participatin...

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Detalles Bibliográficos
Autores principales: Devocelle, Aurore, Lecru, Lola, François, Hélène, Desterke, Christophe, Gallerne, Cindy, Eid, Pierre, Estelle, Oberlin, Azzarone, Bruno, Giron-Michel, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642769/
https://www.ncbi.nlm.nih.gov/pubmed/31360169
http://dx.doi.org/10.1155/2019/9151394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642769/
https://www.ncbi.nlm.nih.gov/pubmed/31360169
http://dx.doi.org/10.1155/2019/9151394

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