Transcription preinitiation complex structure and dynamics provide insight into genetic diseases

Transcription pre-initiation complexes (PIC) are vital assemblies whose function underlies protein gene expression. Cryo-EM advances have begun to uncover their structural organization. Yet, functional analyses are hindered by incompletely modeled regions. Here we integrate all available cryo-EM dat...

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Detalles Bibliográficos
Autores principales: Yan, Chunli, Dodd, Thomas, He, Yuan, Tainer, John A., Tsutakawa, Susan E., Ivanov, Ivaylo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642811/
https://www.ncbi.nlm.nih.gov/pubmed/31110295
http://dx.doi.org/10.1038/s41594-019-0220-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642811/
https://www.ncbi.nlm.nih.gov/pubmed/31110295
http://dx.doi.org/10.1038/s41594-019-0220-3

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