Cargando…
Transcription preinitiation complex structure and dynamics provide insight into genetic diseases
Transcription pre-initiation complexes (PIC) are vital assemblies whose function underlies protein gene expression. Cryo-EM advances have begun to uncover their structural organization. Yet, functional analyses are hindered by incompletely modeled regions. Here we integrate all available cryo-EM dat...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642811/ https://www.ncbi.nlm.nih.gov/pubmed/31110295 http://dx.doi.org/10.1038/s41594-019-0220-3 |