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PRDM9 forms a trimer by interactions within the zinc finger array

PRDM9 is a trans-acting factor directing meiotic recombination to specific DNA-binding sites by its zinc finger (ZnF) array. It was suggested that PRDM9 is a multimer; however, we do not know the stoichiometry or the components inducing PRDM9 multimerization. In this work, we used in vitro binding s...

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Detalles Bibliográficos
Autores principales: Schwarz, Theresa, Striedner, Yasmin, Horner, Andreas, Haase, Karin, Kemptner, Jasmin, Zeppezauer, Nicole, Hermann, Philipp, Tiemann-Boege, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643046/
https://www.ncbi.nlm.nih.gov/pubmed/31308055
http://dx.doi.org/10.26508/lsa.201800291