Cargando…
PRDM9 forms a trimer by interactions within the zinc finger array
PRDM9 is a trans-acting factor directing meiotic recombination to specific DNA-binding sites by its zinc finger (ZnF) array. It was suggested that PRDM9 is a multimer; however, we do not know the stoichiometry or the components inducing PRDM9 multimerization. In this work, we used in vitro binding s...
Autores principales: | Schwarz, Theresa, Striedner, Yasmin, Horner, Andreas, Haase, Karin, Kemptner, Jasmin, Zeppezauer, Nicole, Hermann, Philipp, Tiemann-Boege, Irene |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643046/ https://www.ncbi.nlm.nih.gov/pubmed/31308055 http://dx.doi.org/10.26508/lsa.201800291 |
Ejemplares similares
-
The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence
por: Striedner, Yasmin, et al.
Publicado: (2017) -
The consequences of sequence erosion in the evolution of recombination hotspots
por: Tiemann-Boege, Irene, et al.
Publicado: (2017) -
PRDM9 points the zinc finger at meiotic recombination hotspots
por: Neale, Matthew J
Publicado: (2010) -
Diversity of Prdm9 Zinc Finger Array in Wild Mice Unravels New Facets of the Evolutionary Turnover of this Coding Minisatellite
por: Buard, Jérôme, et al.
Publicado: (2014) -
PRDM9 sticks its zinc fingers into recombination hotspots and between species
por: Sandovici, Ionel, et al.
Publicado: (2010)