The antitumor properties of metformin and phenformin reflect their ability to inhibit the actions of differentiated embryo chondrocyte 1

BACKGROUND: Differentiated embryo chondrocyte 1 (DEC1) is a helix-loop-helix transcription factor that directly binds to the class B E-box in target genes. DEC1 exerts both pro-survival and pro-apoptotic effects in a cell- and tissue-dependent manner. Its actions play role the progression of cancer...

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Detalles Bibliográficos
Autores principales: Kuo, Chun-Lin, Hsieh Li, Shu-Man, Liang, Shu-Yi, Liu, Shu-Ting, Huang, Li-Chun, Wang, Wei-Ming, Yen, Li-Chen, Huang, Shih-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643064/
https://www.ncbi.nlm.nih.gov/pubmed/31410055
http://dx.doi.org/10.2147/CMAR.S210637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643064/
https://www.ncbi.nlm.nih.gov/pubmed/31410055
http://dx.doi.org/10.2147/CMAR.S210637

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