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Long-term Pilocarpine Treatment Improves Salivary Flow in Irradiated Mice

Radiation therapy for head and neck cancer frequently causes salivary gland dysfunction. Pilocarpine is a clinically approved and effective drug that induces saliva secretion, thereby keeping the oral mucosa moist and reducing discomfort in patients, but the effect is transient. We expected that thi...

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Detalles Bibliográficos
Autores principales: Taniguchi, Akie, Susa, Taketo, Kogo, Hiroshi, Iizuka-Kogo, Akiko, Yokoo, Satoshi, Matsuzaki, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643095/
https://www.ncbi.nlm.nih.gov/pubmed/31341340
http://dx.doi.org/10.1267/ahc.19006