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Anti-Tumor Activity and Pharmacokinetics of AP25-Fc Fusion Protein

AP25 is an anti-tumor peptide with a high affinity for integrins. It exerts its anti-tumor activity by inhibiting angiogenesis and by directly inhibiting the growth of tumor cells. Its half-life time in vivo is only about 50 minutes, which limits its clinical application. In order to prolong the hal...

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Detalles Bibliográficos
Autores principales: Pei, Dening, Hu, Jialiang, Rao, Chunming, Yu, Pengcheng, Xu, Hanmei, Wang, Junzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643120/
https://www.ncbi.nlm.nih.gov/pubmed/31341417
http://dx.doi.org/10.7150/ijms.34365