Metformin Inhibits Epithelial-to-Mesenchymal Transition of Keloid Fibroblasts via the HIF-1α/PKM2 Signaling Pathway

Background: Epithelial-to-mesenchymal transition (EMT) is a process whereby epithelial cells lose cell-cell contacts and acquire expression of mesenchymal components and manifest a migratory phenotype. Recent studies indicated that EMT is involved in the development of keloids. Therefore, this study...

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Detalles Bibliográficos
Autores principales: Lei, Rui, Zhang, Shizhen, Wang, Yuming, Dai, Siya, Sun, Jiaqi, Zhu, Chaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643126/
https://www.ncbi.nlm.nih.gov/pubmed/31341409
http://dx.doi.org/10.7150/ijms.32157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643126/
https://www.ncbi.nlm.nih.gov/pubmed/31341409
http://dx.doi.org/10.7150/ijms.32157

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