Cargando…
Metformin Inhibits Epithelial-to-Mesenchymal Transition of Keloid Fibroblasts via the HIF-1α/PKM2 Signaling Pathway
Background: Epithelial-to-mesenchymal transition (EMT) is a process whereby epithelial cells lose cell-cell contacts and acquire expression of mesenchymal components and manifest a migratory phenotype. Recent studies indicated that EMT is involved in the development of keloids. Therefore, this study...
Autores principales: | Lei, Rui, Zhang, Shizhen, Wang, Yuming, Dai, Siya, Sun, Jiaqi, Zhu, Chaoqun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643126/ https://www.ncbi.nlm.nih.gov/pubmed/31341409 http://dx.doi.org/10.7150/ijms.32157 |
Ejemplares similares
-
Metformin inhibits epithelial-mesenchymal transition of oral squamous cell carcinoma via the mTOR/HIF-1α/PKM2/STAT3 pathway
por: Yin, Weihuang, et al.
Publicado: (2021) -
Epithelial-mesenchymal transition in keloid tissue
por: Yang, Chae-Eun, et al.
Publicado: (2018) -
Examination of Epithelial Mesenchymal Transition in Keloid Tissues and Possibility of Keloid Therapy Target
por: Kuwahara, Hiroaki, et al.
Publicado: (2016) -
Multitranscriptome analyses of keloid fibroblasts reveal the role of the HIF-1α/HOXC6/ERK axis in keloid development
por: Wang, Qi, et al.
Publicado: (2022) -
PTB Regulates the Metabolic Pathways and Cell Function of Keloid Fibroblasts through Alternative Splicing of PKM
por: Huang, Rong, et al.
Publicado: (2023)