Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA(2)β/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 β-cells

Aims: Berberine (BBR) improves beta-cell function in Type 2 diabetes (T2D) because of its anti-apoptotic activity, and our laboratory developed a new preparation named Huang-Gui Solid Dispersion (HGSD) to improve the oral bioavailability of BBR. However, the mechanism by which BBR inhibits beta-cell...

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Detalles Bibliográficos
Autores principales: Li, Junnan, Du, Hongwei, Zhang, Meishuang, Zhang, Zhi, Teng, Fei, Zhao, Yali, Zhang, Wenyou, Yu, Yang, Feng, Linjing, Cui, Xinming, Zhang, Ming, Lu, Tzongshi, Guan, Fengying, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643135/
https://www.ncbi.nlm.nih.gov/pubmed/31337982
http://dx.doi.org/10.7150/ijbs.32020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643135/
https://www.ncbi.nlm.nih.gov/pubmed/31337982
http://dx.doi.org/10.7150/ijbs.32020

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