The CtBP1-HDAC1/2-IRF1 transcriptional complex represses the expression of the long noncoding RNA GAS5 in human osteosarcoma cells

Growth Arrest Specific 5 (GAS5), a long noncoding RNA (lncRNA), functions as a tumor suppressor in multiple cancers. However, its function, downstream targets and upstream regulatory mechanism are still obscure in osteosarcoma cells. Here, we discovered that GAS5 was downregulated in cancerous osteo...

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Detalles Bibliográficos
Autores principales: Zhang, Xinliang, Du, Kaili, Lou, Zhenkai, Ding, Keyuan, Zhang, Fan, Zhu, Jinwen, Chang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643137/
https://www.ncbi.nlm.nih.gov/pubmed/31337976
http://dx.doi.org/10.7150/ijbs.33529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643137/
https://www.ncbi.nlm.nih.gov/pubmed/31337976
http://dx.doi.org/10.7150/ijbs.33529

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