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Specifically blocking the fatty acid synthesis to inhibit the malignant phenotype of bladder cancer

Fatty acid synthesis is regulated by transcription factors SREBPs and their escort protein SCAP. Malignant cells become dependent on de novo lipogenesis, which sustains rapid proliferation and resistance to cellular stress. Increasing evidence showed SCAP participated in various disease processes in...

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Detalles Bibliográficos
Autores principales: Li, Aolin, Yao, Lin, Fang, Yuan, Yang, Kang, Jiang, Wei, Huang, Weiren, Cai, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643213/
https://www.ncbi.nlm.nih.gov/pubmed/31360104
http://dx.doi.org/10.7150/ijbs.32518