TLX3 repressed SNAI1-induced epithelial-mesenchymal transition by directly constraining STAT3 phosphorylation and functionally sensitized 5-FU chemotherapy in hepatocellular carcinoma

TLX3 has an established role as a sequence-specific transcription factor with vital functions in the nervous system. Although several studies have shown that TLX3 is aberrantly up-regulated in leukemia, its expression and function in hepatocellular carcinoma (HCC) remain unknown. We found that TLX3...

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Detalles Bibliográficos
Autores principales: Wang, Cong, Dou, Changwei, Wang, Yufeng, Liu, Zhikui, Roberts, Lewis, Zheng, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643223/
https://www.ncbi.nlm.nih.gov/pubmed/31360112
http://dx.doi.org/10.7150/ijbs.33844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643223/
https://www.ncbi.nlm.nih.gov/pubmed/31360112
http://dx.doi.org/10.7150/ijbs.33844

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