Cargando…
TLX3 repressed SNAI1-induced epithelial-mesenchymal transition by directly constraining STAT3 phosphorylation and functionally sensitized 5-FU chemotherapy in hepatocellular carcinoma
TLX3 has an established role as a sequence-specific transcription factor with vital functions in the nervous system. Although several studies have shown that TLX3 is aberrantly up-regulated in leukemia, its expression and function in hepatocellular carcinoma (HCC) remain unknown. We found that TLX3...
Autores principales: | Wang, Cong, Dou, Changwei, Wang, Yufeng, Liu, Zhikui, Roberts, Lewis, Zheng, Xin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643223/ https://www.ncbi.nlm.nih.gov/pubmed/31360112 http://dx.doi.org/10.7150/ijbs.33844 |
Ejemplares similares
-
cJun phosphorylation integrates calcium spike activity and tlx3 expression to regulate neurotransmitter specification
por: Marek, Kurt W., et al.
Publicado: (2010) -
Hyperactivation of IL-6/STAT3 pathway leaded to the poor prognosis of post-TACE HCCs by HIF-1α/SNAI1 axis-induced epithelial to mesenchymal transition
por: Gai, Xiaohong, et al.
Publicado: (2020) -
Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia
por: Vanden Bempt, Marlies, et al.
Publicado: (2018) -
Snai1 represses Nanog to promote embryonic stem cell differentiation
por: Galvagni, F., et al.
Publicado: (2015) -
Deletion of Snai2 and Snai3 Results in Impaired Physical Development Compounded by Lymphocyte Deficiency
por: Pioli, Peter D., et al.
Publicado: (2013)