Inhibition of super enhancer downregulates the expression of KLF5 in basal-like breast cancers

The transcription factor KLF5 (Krüpple-like factor 5) is highly expressed in basal-like breast cancer (BLBC), which promotes cell proliferation, survival, migration and stemness, serving as a potential therapeutic target. In the current study, a super-enhancer (SE) was identified to be located downs...

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Detalles Bibliográficos
Autores principales: Chen, Chuan-Huizi, Yang, Nong, Zhang, Yongchang, Ding, Jiancheng, Zhang, Wenjuan, Liu, Rong, Liu, Wen, Chen, Ceshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643226/
https://www.ncbi.nlm.nih.gov/pubmed/31360115
http://dx.doi.org/10.7150/ijbs.35138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643226/
https://www.ncbi.nlm.nih.gov/pubmed/31360115
http://dx.doi.org/10.7150/ijbs.35138

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