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Plumbagin promotes human hepatoma SMMC-7721 cell apoptosis via caspase-3/vimentin signal-mediated EMT

BACKGROUND/AIMS: Plumbagin (PL) has been shown to effectively inhibit tumor growth and migration of hepatocellular carcinoma cells in previous studies, but the specific mechanism for this remains unclear. The purpose of this study was to investigate the effects of PL-induced apoptosis in epithelial–...

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Detalles Bibliográficos
Autores principales: Wei, Yanfei, Lv, Beibei, Xie, Jinling, Zhang, Yuan, Lin, Yuning, Wang, Shengshan, Zhong, Jing, Chen, Yongxin, Peng, Yue, Ma, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643260/
https://www.ncbi.nlm.nih.gov/pubmed/31409969
http://dx.doi.org/10.2147/DDDT.S204787