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Solution‐Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies
Amyloid β‐peptides (Aβ) play a major role in the pathogenesis of Alzheimer's disease. Therefore, numerous monoclonal antibodies against Aβ have been developed for basic and clinical research. The present study applied fluorescence based analytical ultracentrifugation and microscale thermophores...
Autores principales: | Zhang, Tao, Nagel‐Steger, Luitgard, Willbold, Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643301/ https://www.ncbi.nlm.nih.gov/pubmed/31367507 http://dx.doi.org/10.1002/open.201900167 |
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