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IL-22 production of effector CD4(+) T-cells is altered in SLE patients

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by T-cell-dependent B-cell activation and altered T-cell response. Co-stimulatory and co-inhibitory molecules regulate and exert T-cell differentiation, survival and cytokine production. CD134(+) and PD-1(+) T-cell...

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Detalles Bibliográficos
Autores principales: Dolff, Sebastian, Scharpenberg, Claudia, Specker, Christof, Kribben, Andreas, Witzke, Oliver, Wilde, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643306/
https://www.ncbi.nlm.nih.gov/pubmed/31331400
http://dx.doi.org/10.1186/s40001-019-0385-6