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IL-22 production of effector CD4(+) T-cells is altered in SLE patients
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by T-cell-dependent B-cell activation and altered T-cell response. Co-stimulatory and co-inhibitory molecules regulate and exert T-cell differentiation, survival and cytokine production. CD134(+) and PD-1(+) T-cell...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643306/ https://www.ncbi.nlm.nih.gov/pubmed/31331400 http://dx.doi.org/10.1186/s40001-019-0385-6 |