The design, analysis and application of mouse clinical trials in oncology drug development

BACKGROUND: Mouse clinical trials (MCTs) are becoming wildly used in pre-clinical oncology drug development, but a statistical framework is yet to be developed. In this study, we establish such as framework and provide general guidelines on the design, analysis and application of MCTs. METHODS: We s...

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Detalles Bibliográficos
Autores principales: Guo, Sheng, Jiang, Xiaoqian, Mao, Binchen, Li, Qi-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643318/
https://www.ncbi.nlm.nih.gov/pubmed/31331301
http://dx.doi.org/10.1186/s12885-019-5907-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643318/
https://www.ncbi.nlm.nih.gov/pubmed/31331301
http://dx.doi.org/10.1186/s12885-019-5907-7

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