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Bacteriophage MS2 As a Tool for Targeted Delivery in Solid Tumor Chemotherapy

Bacteriophage MS2 was employed for targeted delivery of an apoptosis-inducing agent, Tl+, into a tumor tissue. The targeted delivery was ensured by iRGD peptide, a ligand of integrins presumably located on the surface of endotheliocytes of the tumor tissue neovasculature and certain tumor cells. The...

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Detalles Bibliográficos
Autores principales: Kolesanova, E. F., Melnikova, M. V., Bolshakova, T. N., Rybalkina, E. Yu., Sivov, I. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643345/
https://www.ncbi.nlm.nih.gov/pubmed/31413886
http://dx.doi.org/10.32607/20758251-2019-11-2-98-101