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CDYL promotes the chemoresistance of small cell lung cancer by regulating H3K27 trimethylation at the CDKN1C promoter

Rationale: Chemoresistance frequently occurs in patients with small cell lung cancer (SCLC) and leads to a dismal prognosis. However, the mechanisms underlying this process remain largely unclear. Methods: The effects of chromodomain Y-like (CDYL) on chemoresistance in SCLC were determined using Wes...

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Detalles Bibliográficos
Autores principales: Qiu, Zhengang, Zhu, Weiliang, Meng, Hui, Tong, Lihua, Li, Xi, Luo, Peng, Yi, Lilan, Zhang, Xiaoli, Guo, Linlang, Wei, Ting, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643436/
https://www.ncbi.nlm.nih.gov/pubmed/31367252
http://dx.doi.org/10.7150/thno.33680