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Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities

Rationale: Osteoporosis is a severe bone disorder that is a threat to our aging population. Excessive osteoclast formation and bone resorption lead to changes in trabecular bone volume and architecture, leaving the bones vulnerable to fracture. Therapeutic approaches of inhibiting osteoclastogenesis...

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Detalles Bibliográficos
Autores principales: Liu, Yuhao, Wang, Chao, Wang, Gang, Sun, Youqiang, Deng, Zhangrong, Chen, Leilei, Chen, Kai, Tickner, Jennifer, Kenny, Jacob, Song, Dezhi, Zhang, Qingwen, Wang, Haibin, Chen, Zhenqiu, Zhou, Chi, He, Wei, Xu, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643439/
https://www.ncbi.nlm.nih.gov/pubmed/31367247
http://dx.doi.org/10.7150/thno.35414