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Diastereoselective Ring Homologation of Bicyclic Hydrazines: Access to cis-1,3-Diaminocyclohexitols

[Image: see text] A sequence of oxidative cleavage/double nitroaldol condensation followed by a few simple synthetic transformations can lead to polyhydroxylated di- and triaminocyclohexanes from a readily available bicyclic hydrazine. This new synthetic route provides a simple and general access to...

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Detalles Bibliográficos
Autores principales: Blond, Aurélie, Turcaud, Serge, Lecourt, Thomas, Micouin, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643457/
https://www.ncbi.nlm.nih.gov/pubmed/31458191
http://dx.doi.org/10.1021/acsomega.8b02910