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Total Synthesis of Callyspongiolide: An Anticancer Marine Natural Product

[Image: see text] The stereoselective total synthesis of cytotoxic marine macrolide callyspongiolide has been reported. The 14-membered macrolactone ring along with Z-olefin in the molecule was constructed via an intramolecular Horner–Wadsworth–Emmons olefination in a Z-selective fashion. The other...

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Detalles Bibliográficos
Autores principales: Sharma, Ashish, Athe, Sudhakar, Ghosh, Subhash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643460/
https://www.ncbi.nlm.nih.gov/pubmed/31458289
http://dx.doi.org/10.1021/acsomega.8b02156