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Tyrosine Rotamer States in Beta Amyloid: Signatures of Aggregation and Fibrillation
[Image: see text] During the early stages of β amyloid (Ab) peptide aggregation, toxic oligomers form which have been recognized as a likely cause of Alzheimer’s disease. In this work, we use fully atomistic molecular dynamics simulation to study the amorphous aggregation of the peptide as well as m...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643746/ https://www.ncbi.nlm.nih.gov/pubmed/31458243 http://dx.doi.org/10.1021/acsomega.8b02408 |