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Effect of Weakly Interacting Cosolutes on Lysozyme Conformations

[Image: see text] Exposure of a protein to cosolutes, like denaturants, changes its folding equilibrium. To determine the ensemble of protein conformations at equilibrium, in the presence of weakly interacting cosolutes, we present a two-stage analysis of solution X-ray scattering data. In the first...

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Detalles Bibliográficos
Autores principales: Levartovsky, Yehonatan, Shemesh, Asaf, Asor, Roi, Raviv, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643829/
https://www.ncbi.nlm.nih.gov/pubmed/31458260
http://dx.doi.org/10.1021/acsomega.8b01289