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Computational Inference Software for Tetrad Assembly from Randomly Arrayed Yeast Colonies

We describe an information-theory-based method and associated software for computationally identifying sister spores derived from the same meiotic tetrad. The method exploits specific DNA sequence features of tetrads that result from meiotic centromere and allele segregation patterns. Because the me...

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Detalles Bibliográficos
Autores principales: Sakhanenko, Nikita A., Cromie, Gareth A., Dudley, Aimée M., Galas, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643883/
https://www.ncbi.nlm.nih.gov/pubmed/31109921
http://dx.doi.org/10.1534/g3.119.400166