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NLRP3, NLRP12, and IFI16 Inflammasomes Induction and Caspase-1 Activation Triggered by Virulent HSV-1 Strains Are Associated With Severe Corneal Inflammatory Herpetic Disease

The crosstalk between the host's inflammasome system and the invading virulent/less-virulent viruses determines the outcome of the ensuing inflammatory response. An appropriate activation of inflammasomes triggers antiviral inflammatory responses that clear the virus and heal the inflamed tissu...

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Detalles Bibliográficos
Autores principales: Coulon, Pierre-Gregoire, Dhanushkodi, Nisha, Prakash, Swayam, Srivastava, Ruchi, Roy, Soumyabrata, Alomari, Nuha I., Nguyen, Angela M., Warsi, Wasay R., Ye, Caitlin, Carlos-Cruz, Edgar A., Mai, Uyen T., Cruel, Audrey C., Ekmekciyan, Keysi M., Pearlman, Eric, BenMohamed, Lbachir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644090/
https://www.ncbi.nlm.nih.gov/pubmed/31367214
http://dx.doi.org/10.3389/fimmu.2019.01631