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In silico evaluation of apoptogenic potential and toxicological profile of triterpenoids

AIM: Caspases-3 and 8 are key mediators of intrinsic and extrinsic pathway of apoptosis, respectively. Triterpenoids of natural and synthetic origin reported as anticancer agents with apoptotic potential and hence may prove to be good candidates for in silico testing against caspases-3 and 8. MATERI...

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Detalles Bibliográficos
Autores principales: Desai, Tanvi Himanshu, Joshi, Shrikant Vijayrao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644186/
https://www.ncbi.nlm.nih.gov/pubmed/31391686
http://dx.doi.org/10.4103/ijp.IJP_90_18