Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway

This study investigated the effect of acylated synthetic ghrelin (AG) on the survival and proliferation of human chemosensitive ovarian cancer cells (A2780) and explored some mechanisms of action with a focus on the p53 apoptotic pathway and PI3K/Akt and NF-κB survival pathways. Human A2780 ovarian...

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Detalles Bibliográficos
Autores principales: El-kott, Attalla Farag, Shati, Ali A., Al-kahtani, Mohammed Ali, Alqahtani, Sultan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644235/
https://www.ncbi.nlm.nih.gov/pubmed/31360627
http://dx.doi.org/10.1155/2019/9627810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644235/
https://www.ncbi.nlm.nih.gov/pubmed/31360627
http://dx.doi.org/10.1155/2019/9627810

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