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Enhanced Solubility of Telmisartan Phthalic Acid Cocrystals within the pH Range of a Systemic Absorption Site

[Image: see text] Telmisartan (TLM), a nonpeptide angiotensin II antagonist, is widely prescribed for treating arterial hypertension and marketed by the innovator with the trade name of Micardis and Micardis plus. Telmisartan exhibits low aqueous solubility in the pH range of 3–7, which is the physi...

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Detalles Bibliográficos
Autores principales: Kundu, Sudeshna, Kumari, Nimmy, Soni, Saundray Raj, Ranjan, Subham, Kumar, Rajan, Sharon, Ashoke, Ghosh, Animesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644309/
https://www.ncbi.nlm.nih.gov/pubmed/31458196
http://dx.doi.org/10.1021/acsomega.8b02144