Structural Motif Descriptors as a Way To Elucidate the Agonistic or Antagonistic Activity of Growth Hormone–Releasing Hormone Peptide Analogues

[Image: see text] The synthesis of analogues of hypothalamic neuropeptide growth hormone–releasing hormone (GHRH) is an efficient strategy for designing new therapeutic agents. Several promising synthetic agonist and antagonist analogues of GHRH have been developed based on amino acid mutations of t...

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Detalles Bibliográficos
Autores principales: Jeanne Dit Fouque, Kevin, Salgueiro, Luis M., Cai, Renzhi, Sha, Wei, Schally, Andrew V., Fernandez-Lima, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644384/
https://www.ncbi.nlm.nih.gov/pubmed/31458901
http://dx.doi.org/10.1021/acsomega.8b00375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644384/
https://www.ncbi.nlm.nih.gov/pubmed/31458901
http://dx.doi.org/10.1021/acsomega.8b00375

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