Cargando…

Structural Motif Descriptors as a Way To Elucidate the Agonistic or Antagonistic Activity of Growth Hormone–Releasing Hormone Peptide Analogues

[Image: see text] The synthesis of analogues of hypothalamic neuropeptide growth hormone–releasing hormone (GHRH) is an efficient strategy for designing new therapeutic agents. Several promising synthetic agonist and antagonist analogues of GHRH have been developed based on amino acid mutations of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeanne Dit Fouque, Kevin, Salgueiro, Luis M., Cai, Renzhi, Sha, Wei, Schally, Andrew V., Fernandez-Lima, Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644384/ https://www.ncbi.nlm.nih.gov/pubmed/31458901 http://dx.doi.org/10.1021/acsomega.8b00375

Ejemplares similares

Growth hormone-releasing hormone agonist attenuates vascular calcification in diabetic db/db mice
por: Ren, Hao-Lin, et al.
Publicado: (2023)

Agonist of growth hormone-releasing hormone improves the disease features of spinal muscular atrophy mice
por: Boido, Marina, et al.
Publicado: (2023)

SAT-603 Growth Hormone-Releasing Hormone (GHRH) Antagonists Stimulate Feeding in Mice
por: Leone, Sheila, et al.
Publicado: (2020)

Antagonistic analogs of growth hormone-releasing hormone increase the efficacy of treatment of triple negative breast cancer in nude mice with doxorubicin; A preclinical study
por: Perez, Roberto, et al.
Publicado: (2014)

Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin
por: Zhang, Chongxu, et al.
Publicado: (2019)

Antagonist of Growth Hormone-Releasing Hormone Potentiates the Antitumor Effect of Pemetrexed and Cisplatin in Pleural Mesothelioma
por: Gesmundo, Iacopo, et al.
Publicado: (2022)

Antagonists of growth hormone-releasing hormone (GHRH) inhibit the growth of human malignant pleural mesothelioma
por: Villanova, Tania, et al.
Publicado: (2019)

Growth hormone-releasing hormone (GHRH) and its agonists inhibit hepatic and tumoral secretion of IGF-1
por: Cui, Tengjiao, et al.
Publicado: (2018)

Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease
por: Zhang, Chongxu, et al.
Publicado: (2020)

Activity of the growth hormone‐releasing hormone antagonist MIA602 and its underlying mechanisms of action in sarcoidosis‐like granuloma
por: Zhang, Chongxu, et al.
Publicado: (2021)

Involvement of the unfolded protein response in the protective effects of growth hormone releasing hormone antagonists in the lungs
por: Akhter, Mohammad S., et al.
Publicado: (2020)

Agonistic analogs of growth hormone releasing hormone (GHRH) promote wound healing by stimulating the proliferation and survival of human dermal fibroblasts through ERK and AKT pathways
por: Cui, Tengjiao, et al.
Publicado: (2016)

Antagonists of Growth Hormone-Releasing Hormone Inhibit the Growth of Pituitary Adenoma Cells by Hampering Oncogenic Pathways and Promoting Apoptotic Signaling
por: Gesmundo, Iacopo, et al.
Publicado: (2021)

Inhibition of in vivo proliferation of androgen-independent prostate cancers by an antagonist of growth hormone-releasing hormone.
por: Jungwirth, A., et al.
Publicado: (1997)

Antinflammatory, antioxidant, and behavioral effects induced by administration of growth hormone-releasing hormone analogs in mice
por: Recinella, Lucia, et al.
Publicado: (2020)

Protective effects of growth hormone-releasing hormone analogs in DSS-induced colitis in mice
por: Recinella, Lucia, et al.
Publicado: (2021)

Antiproliferative effect of growth hormone-releasing hormone (GHRH) antagonist on ovarian cancer cells through the EGFR-Akt pathway
por: Guo, Jian, et al.
Publicado: (2010)

Growth Hormone-Releasing Hormone in Diabetes
por: Fridlyand, Leonid E., et al.
Publicado: (2016)

Publisher Correction: Antinflammatory, antioxidant, and behavioral effects induced by administration of growth hormone-releasing hormone analogs in mice
por: Recinella, Lucia, et al.
Publicado: (2020)

Antagonists of growth hormone-releasing hormone suppress in vivo tumor growth and gene expression in triple negative breast cancers
por: Perez, Roberto, et al.
Publicado: (2012)

Protective effects of agonists of growth hormone-releasing hormone (GHRH) in early experimental diabetic retinopathy
por: Thounaojam, Menaka C., et al.
Publicado: (2017)

Growth hormone-releasing hormone antagonist MIA-602 inhibits inflammation induced by SARS-CoV-2 spike protein and bacterial lipopolysaccharide synergism in macrophages and human peripheral blood mononuclear cells
por: Granato, Giuseppina, et al.
Publicado: (2023)

Growth Hormone–Releasing Hormone Agonists Reduce Myocardial Infarct Scar in Swine With Subacute Ischemic Cardiomyopathy
por: Bagno, Luiza L., et al.
Publicado: (2015)

Growth hormone releasing hormone induces the expression of nitric oxide synthase
por: Barabutis, Nektarios, et al.
Publicado: (2011)

A change from gonadotropin releasing hormone antagonist to gonadotropin releasing hormone agonist therapy does not affect the oncological outcomes in hormone sensitive prostate cancer
por: Asakawa, Jumpei, et al.
Publicado: (2018)

Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction
por: Czikora, Istvan, et al.
Publicado: (2014)

Hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin-releasing hormone agonist and a dopamine antagonist
por: Trudeau, Vance L, et al.
Publicado: (2010)

Growth hormone–releasing hormone receptor antagonist MIA-602 attenuates cardiopulmonary injury induced by BSL-2 rVSV-SARS-CoV-2 in hACE2 mice
por: Condor Capcha, Jose M., et al.
Publicado: (2023)

Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers
por: Szepeshazi, K, et al.
Publicado: (2000)

Growth hormone-releasing hormone antagonist inhibits the invasiveness of human endometrial cancer cells by down-regulating twist and N-cadherin expression
por: Wu, Hsien-Ming, et al.
Publicado: (2016)

Comparison of clinical outcomes between the depot gonadotrophin-releasing hormone agonist protocol and gonadotrophin-releasing hormone antagonist protocol in normal ovarian responders
por: Xia, Min, et al.
Publicado: (2021)

A randomized controlled trial of gonadotropin-releasing hormone agonist versus gonadotropin-releasing hormone antagonist in Iranian infertile couples: oocyte gene expression
por: Hoseini, Fatemeh Sadat, et al.
Publicado: (2014)

Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Has the Same Effect as Gonadotropin-Releasing Hormone Agonist Injections in Terms of Preparation for Transcervical Resection Myomectomy
por: Ito, Mika, et al.
Publicado: (2022)

Knocking down gene expression for growth hormone-releasing hormone inhibits proliferation of human cancer cell lines
por: Barabutis, N, et al.
Publicado: (2008)

Comparative proteomics reveal negative effects of gonadotropin-releasing hormone agonist and antagonist on human endometrium
por: Chen, Qian, et al.
Publicado: (2019)

Editorial Comment to Considerations for the use of gonadotropin‐releasing hormone agonists and antagonists in patients with prostate cancer
por: Kawahara, Takashi
Publicado: (2020)

Growth Hormone-Releasing Hormone and Its Analogues: Significance for MSCs-Mediated Angiogenesis
por: Xia, Xiangyang, et al.
Publicado: (2016)

Gonadotropin-Releasing Hormone Analogue Stimulation Test Versus Venous Sampling in Postmenopausal Hyperandrogenism
por: Tng, Eng-Loon, et al.
Publicado: (2020)

Gonadotrophin releasing hormone antagonist in IVF/ICSI
por: MS, Kamath, et al.
Publicado: (2008)

Gonadotropin releasing hormone agonists: Expanding vistas
por: Magon, Navneet
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ccbuppo45ifp0dqmudb5m6sr4j