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Unusual Nucleophilic Addition of Grignard Reagents in the Synthesis of 4-Amino-pyrimidines

[Image: see text] Pyrimidines have always received considerable attention because of their importance in synthesis and elucidation of biochemical roles, in particular that of vitamin B1. Herein, we describe a reaction pathway in a Grignard reagent-based synthesis of substituted pyrimidines. A genera...

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Detalles Bibliográficos
Autores principales: Tinson, Ryan A. J., Hughes, David L., Ward, Leanne, Stephenson, G. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644423/
https://www.ncbi.nlm.nih.gov/pubmed/31459026
http://dx.doi.org/10.1021/acsomega.8b01137