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Combretastatin-Inspired Heterocycles as Antitubulin Anticancer Agents
[Image: see text] Combretastatin (CA-4) and its analogues are undergoing several clinical trials for treating different types of tumors. In this work, the antiproliferative activity of a series of 2-aminoimidazole-carbonyl analogs of clinically relevant combretastatins A-4 (CA-4) and A-1 was evaluat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644768/ https://www.ncbi.nlm.nih.gov/pubmed/31459105 http://dx.doi.org/10.1021/acsomega.8b00996 |