Highly Enantioselective One-Pot Synthesis of Chiral β-Heterosubstituted Alcohols via Ruthenium–Prolinamide-Catalyzed Asymmetric Transfer Hydrogenation

[Image: see text] The utility of a chiral Ru–prolinamide catalytic system has been demonstrated in one-pot synthesis of optically active β-triazolylethanol and β-hydroxy sulfone derivatives. The said methodology proceeds through asymmetric transfer hydrogenation of in situ formed ketones of the corr...

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Detalles Bibliográficos
Autores principales: Vyas, Vijyesh K., Srivastava, Prasenjit, Bhatt, Prachi, Shende, Vaishali, Ghosh, Pushpito, Bhanage, Bhalchandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644779/
https://www.ncbi.nlm.nih.gov/pubmed/31458000
http://dx.doi.org/10.1021/acsomega.8b01316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644779/
https://www.ncbi.nlm.nih.gov/pubmed/31458000
http://dx.doi.org/10.1021/acsomega.8b01316

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