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Tandem Alkylation–Second-Order Asymmetric Transformation Protocol for the Preparation of Phenylalanine-Type Tailor-Made α-Amino Acids

[Image: see text] In this work, we disclose an advanced general process for the synthesis of tailor-made α-amino acids (α-AAs) via tandem alkylation–second-order asymmetric transformation. The first step is the alkylation of the chiral Ni(II) complex of glycine Schiff base, which is conducted under...

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Detalles Bibliográficos
Autores principales: Takeda, Ryosuke, Kawashima, Aki, Yamamoto, Junya, Sato, Tatsunori, Moriwaki, Hiroki, Izawa, Kunisuke, Abe, Hidenori, Soloshonok, Vadim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644829/
https://www.ncbi.nlm.nih.gov/pubmed/31459102
http://dx.doi.org/10.1021/acsomega.8b01424