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Synthesis of 1,2,4-Trisubstituted-(1H)-imidazoles through Cu(OTf)(2)-/I(2)-Catalyzed C–C Bond Cleavage of Chalcones and Benzylamines
[Image: see text] 1,2,4-Trisubstituted-(1H)-imidazoles have been synthesized by the Cu(OTf)(2)- and I(2)-catalyzed unusual C–C bond cleavage of chalcones and benzylamines. After the α,β-unsaturated C–C bond cleavage, the β-portion is eliminated from the reaction. Various aryl- and heteroaryl-substit...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644843/ https://www.ncbi.nlm.nih.gov/pubmed/31458944 http://dx.doi.org/10.1021/acsomega.8b01017 |