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Synthesis of 1,2,4-Trisubstituted-(1H)-imidazoles through Cu(OTf)(2)-/I(2)-Catalyzed C–C Bond Cleavage of Chalcones and Benzylamines

[Image: see text] 1,2,4-Trisubstituted-(1H)-imidazoles have been synthesized by the Cu(OTf)(2)- and I(2)-catalyzed unusual C–C bond cleavage of chalcones and benzylamines. After the α,β-unsaturated C–C bond cleavage, the β-portion is eliminated from the reaction. Various aryl- and heteroaryl-substit...

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Detalles Bibliográficos
Autores principales: Salfeena, Chettiyan Thodi F., Jalaja, Renjitha, Davis, Rincy, Suresh, Eringathodi, Somappa, Sasidhar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644843/
https://www.ncbi.nlm.nih.gov/pubmed/31458944
http://dx.doi.org/10.1021/acsomega.8b01017