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FeCl(3)-Mediated Side Chain Modification of Aspartic Acid- and Glutamic Acid-Containing Peptides on a Solid Support

[Image: see text] An efficient, convenient, and selective Lewis acid-based strategy for on-resin deprotection of the side chain tert-butyl-protected aspartic acid and glutamic acid of a peptide is achieved. The method is mild, cost-effective, and Fmoc chemistry compatible and allows on-resin incorpo...

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Detalles Bibliográficos
Autores principales: Giri, Rajat Subhra, Manne, Srinivasa Rao, Dolai, Gobinda, Paul, Ashim, Kalita, Tapasi, Mandal, Bhubaneswar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644899/
https://www.ncbi.nlm.nih.gov/pubmed/31457256
http://dx.doi.org/10.1021/acsomega.7b01143