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Contrasting Effects of Guanidinium Chloride and Urea on the Activity and Unfolding of Lysozyme
[Image: see text] Cosolvents play an important role in regulating the stability and function of proteins present in the cell. We studied the role of cosolvents, urea and guanidinium chloride (GdmCl), which act as protein denaturants, in the catalytic activity and structural stability of the protein...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644995/ https://www.ncbi.nlm.nih.gov/pubmed/31458105 http://dx.doi.org/10.1021/acsomega.8b01911 |