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Contrasting Effects of Guanidinium Chloride and Urea on the Activity and Unfolding of Lysozyme

[Image: see text] Cosolvents play an important role in regulating the stability and function of proteins present in the cell. We studied the role of cosolvents, urea and guanidinium chloride (GdmCl), which act as protein denaturants, in the catalytic activity and structural stability of the protein...

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Detalles Bibliográficos
Autores principales: Biswas, Biswajit, Muttathukattil, Aswathy N., Reddy, Govardhan, Singh, Prashant Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644995/
https://www.ncbi.nlm.nih.gov/pubmed/31458105
http://dx.doi.org/10.1021/acsomega.8b01911