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Effect of Differences in the Primary Structure of the A-Chain on the Aggregation of Insulin Fragments

[Image: see text] Bovine and human insulin have similar primary structures. In this article, the region of the insulin A-chain of bovine and human insulin where the amino acid composition is different was studied. Bovine insulin fragment (BIF) and human insulin fragment (HIF) were synthesized in sol...

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Detalles Bibliográficos
Autores principales: Nakka, Paul P., Li, Ke, Forciniti, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645046/
https://www.ncbi.nlm.nih.gov/pubmed/31459094
http://dx.doi.org/10.1021/acsomega.8b00500