Circular Dichroistic Impacts of 1-(3-Dimethylaminopropyl)-3-ethylurea: Secondary Structure Artifacts Arising from Bioconjugation Using 1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide

[Image: see text] 1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide (EDC) is a commonly used reagent for bioconjugation and peptide synthesis. Both EDC and the corresponding urea derivative, 1-(3-dimethylaminopropyl)-3-ethylurea (EDU), are achiral. As the reagent is active in aqueous solutions, it is a...

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Detalles Bibliográficos
Autores principales: Kubilius, Matthew B., Tu, Raymond S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645161/
https://www.ncbi.nlm.nih.gov/pubmed/31457370
http://dx.doi.org/10.1021/acsomega.7b01288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645161/
https://www.ncbi.nlm.nih.gov/pubmed/31457370
http://dx.doi.org/10.1021/acsomega.7b01288

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