Synthetic Studies toward the Natural Product Tripartin, the First Natural Histone Lysine Demethylase Inhibitor

[Image: see text] An efficient synthesis of dimethyl tripartin as a synthetic precursor of natural product tripartin, the first natural specific inhibitor of histone H3 lysine 9 demethylase KDM4, is described. The synthesis of dimethyl tripartin was achieved in a six-step longest linear sequence sta...

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Detalles Bibliográficos
Autores principales: Dethe, Dattatraya H., Boda, Raghavender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645238/
https://www.ncbi.nlm.nih.gov/pubmed/31459063
http://dx.doi.org/10.1021/acsomega.8b01341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645238/
https://www.ncbi.nlm.nih.gov/pubmed/31459063
http://dx.doi.org/10.1021/acsomega.8b01341

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