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Computational Study of the Loss-of-Function Mutations in the Kv1.5 Channel Associated with Atrial Fibrillation

[Image: see text] Atrial fibrillation (AF) is a heart disease caused by defective ion channels in the atria, which affect the action potential (AP) duration and disturb normal heart rhythm. Rapid firing of APs in neighboring atrial cells is a common mechanism of AF, and therefore, therapeutic approa...

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Detalles Bibliográficos
Autores principales: Rashid, Md Harunur, Kuyucak, Serdar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645308/
https://www.ncbi.nlm.nih.gov/pubmed/31459020
http://dx.doi.org/10.1021/acsomega.8b01094