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Nonantioxidant Tetramethoxystilbene Abrogates α-Synuclein-Induced Yeast Cell Death but Not That Triggered by the Bax or βA4 Peptide

[Image: see text] The overexpression of α-synuclein (α-syn) and its aggregation is the hallmark of Parkinson’s disease. The α-syn aggregation results in the formation of Lewy bodies that causes neuronal cell death. Therefore, the small molecules that can protect neuronal cells from α-syn toxicity or...

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Detalles Bibliográficos
Autores principales: Derf, Asma, Mudududdla, Ramesh, Akintade, Damilare, Williams, Ibidapo S., Abdullaha, Mohd, Chaudhuri, Bhabatosh, Bharate, Sandip B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645319/
https://www.ncbi.nlm.nih.gov/pubmed/31459084
http://dx.doi.org/10.1021/acsomega.8b01154