Ppm Cu Catalyst Enables tert-Alkylation Followed by C–H Cyclization To Synthesize Substituted Oxindoles

[Image: see text] In this paper, we established highly efficient Cu-catalyzed tandem tert-alkylation C–H cyclization of α-bromocarbonyls and methacrylamides to produce substituted oxindoles. The maximum turnover number was up to 48 000 with reasonable yield. Although the catalyst loadings were very...

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Detalles Bibliográficos
Autores principales: Yoshinaga, Kohei, Tsubaki, Naoya, Murata, Yumi, Noda, Yushi, Nishikata, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645334/
https://www.ncbi.nlm.nih.gov/pubmed/31459034
http://dx.doi.org/10.1021/acsomega.8b01397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645334/
https://www.ncbi.nlm.nih.gov/pubmed/31459034
http://dx.doi.org/10.1021/acsomega.8b01397

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