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Ppm Cu Catalyst Enables tert-Alkylation Followed by C–H Cyclization To Synthesize Substituted Oxindoles
[Image: see text] In this paper, we established highly efficient Cu-catalyzed tandem tert-alkylation C–H cyclization of α-bromocarbonyls and methacrylamides to produce substituted oxindoles. The maximum turnover number was up to 48 000 with reasonable yield. Although the catalyst loadings were very...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645334/ https://www.ncbi.nlm.nih.gov/pubmed/31459034 http://dx.doi.org/10.1021/acsomega.8b01397 |